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182 PROGSTREEN – Megostrol acetate

Oral Hormone Tablets for Dogs and Cats

COMPOSITION:

Each tablet contains:

Megestrol Acetate            5 mg

 

 

INDICATIONS:

PROGSTREEN tablets for dogs and cats contains the megestrol acetate which is used for Oestrus control and treatment of the miliary dermatitis and eosinophilic granuloma (rodent ulcer) in the cats. And postponement or prevention of oestrus and the treatment of false pregnancy and oestrogen

dependent mammary tumours in the bitches. PROGSTREEN tablets used for the prevention of unwanted pregnancy in the female dogs and cats.

PROGSTREEN tablets recommended to administration by the oral route in the male dogs treatment of hyper sexuality which may be manifest as undesirable behavior in male dogs.

 

DOSAGE AND ADMINISTRATION:

Dogs (Female):

  • Postponement of oestrus: (0.5 mg per kg) daily for a maximum period of 40 days as shown in the dosage table. The course of tablets should commence preferably 14 days at least before the oestrus. A series of postponement courses may be given provided the bitch is not medicated more than twice during 12 month period.

  • Weight (Kg) Dose (Tablet 5 mg)
    6 – 10 1
    16 – 20 2
    21 – 30 3
    31 – 40 4
    41 – 50 5

 

Prevention of oestrus (suppression of heat):
For normal dosage regimen: give 2 mg per kg daily for 8 days as shown in the dosage table. The course of tablets should commence at the onset of pro-oestrus by the presence of both haemorrhage and vulval swelling. The stage of the oestrus cycle may be confirmed by the examination of vaginal smears.

Weight (Kg) Dose (Tablet 5 mg)
2.5 – 5 2
6 – 7.5 3
8 – 10 4
11 – 15 6

 

For extended dosage regimen: give 2 mg per kg daily for 4 days followed by 0.5 mg per kg daily for 16 days as shown in the dosage table. The use of this prolonged prevention course is advised in first season bitches, and may also be beneficial in bitches with a history of false pregnancy, in some cases where other abnormalities of the oestrous cycle are known to occur and when the animal to be medicated is housed with other bitches.

 

Weight (Kg) Dose (Tablet 5 mg)
For 4 days
2.5 – 5 2
6 – 7.5 3
8 – 10 4
11 – 15 6
For 16 days
6 – 10 1
16 – 20 2
21 – 30 3
31 – 40 4
41 – 50 5

 

Dogs male:
For undesirable behavior in dogs: Recommended to administration by the oral route given whole or crushed and mixed with food.

  • Initial dosing: 2 mg per kg daily for 7 days.

  • Subsequent dosing:
    Improved: 1 mg per kg daily for 14 days
    Not improved: 4 mg per kg daily for 7 days

Cats Female:

  • Oestrus control:
    Postponement of oestrus: 1 tablet per cat once weekly for up to 15 weeks. Dosage should commence in anoestrus (the non-breeding season).
    Prevention of oestrus: 1 tablet per cat daily for three days, given when the Signs of Desire to mating appear.

  • Treatment of miliary eczema (miliary dermatitis) and eosinophilic granuloma (rodent ulcer) in cats: The recommended dosage is 1 tablet per cat every two to three days until the lesions begin to regress then once weekly until a satisfactory response is obtained. In some cases it may be necessary to give a maintenance dosage of 2.5 mg per cat weekly or fortnightly to prevent recurrence of the condition.

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